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Although a statistically significant reduction was observed in Sequence 2 (i.e., GSH-C4-first) from baseline to the intermediate timepoint (p = 0.0312), only a modest decrease in the FACES score was noted in Sequence 1 (i.e., HA-first) from the intermediate to the final timepoint (p = 0.0625)

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[PubMed ID: 27395781]