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Earlier evaluation is warranted with known risk factors such as irregular menses, amenorrhea lasting more than 3 months, severe male factor, endometriosis, or pelvic disease
This cytotoxicity was attributed to specific motifs, like PSQQ, and was further linked to incomplete mucosal digestion in CD, which allows toxic fragments to persist
The junctional nested pattern predominates
Patients may notice their skin appears more radiant or glowing, though dramatic pigmentation changes are rare during this initial period
This allows bacteria to grow and produce odours
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