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Molecular characterization of manganese superoxide dismutase (MnSOD) from sterlet Acipenser ruthenus and its responses to Aeromonas hydrophila challenge and hypoxia stress

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It remodels the epigenome and protects DNA: By binding to promoter regions and loosening chromatin structure, Epitalon may restore youthful gene expression patterns, enhance DNA repair, and reduce mutation load, positioning it as a precision gene-expression modulator rather than a blunt genetic tool

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doi: 10.1056/NEJM198408093110604 127 LauritzenTFrost-LarsenKLarsenH-WDeckertT

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