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The topical route is the format with the strongest human clinical trial evidence for skin outcomes, from the landmark 1998 Abdulghani study that outperformed both vitamin C and tretinoin to the Finkley skin-thickness data
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Epub 2023/11/30
Primary stem cells or unpretreated cells often fail to achieve the desired therapeutic effect due to poor homing ability, the very low survival rate after transplantation, and cellular senescence or decline in viability during in vitro culture
