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The tradeoff is safety: Melanotan-1s adverse event rate is 812% (primarily mild nausea) versus 3550% for MT2
It can directly participate in physiological reactions within cells and is widely used in food, health products, and cosmetics
Tirzepatide (Mounjaro for diabetes, Zepbound for weight loss) are also sometimes included with GLP1s, although they work a little differently
Researchers have studied an oral version of semaglutide along with another GLP-1 drug, orforglipron (brand name Foundayo), for weight loss
10.3390/pharmaceutics11020073 29 BohleyM.LerouxJ
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