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Intake of sweet foods also decreases in the peri-ovulatory period (42) and protein intake increases in the luteal phase (43)

Metabolomics and lipidomics can identify substrate stress, mitochondrial bottlenecks, amino acid imbalance, redox dysregulation, and systemic drivers such as diabetes or chronic kidney disease ( This review synthesizes recent evidence on key metabolic derangementssubstrate inflexibility, mitochondrial dysfunction, BCAA accumulation, and ketone adaptationin myocardial hypertrophy, and critically examines their potential as clinically interpretable biomarker modules and therapeutic targets, while highlighting the persistent challenges in distinguishing adaptive from maladaptive remodeling and translating pathway signals into practice

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adults attempted to lose weight within the past year

( f ) Size-Exclusion chromatogram of crude anti-FLAG elution