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Thus, once MTHFR has reduced 5,10-methyleneTHF to 5-MTHF, the Vitamin B12 dependent methionine synthase, encoded by MTR, uses this reduced folate to convert Hcy back into methionine
A study of elderly patients with dementia revealed drug related somnolence and discontinuation for somnolence [seeWarnings and Precautions (5.14)]
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Fraser, G.E
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