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doi: 10.1177/08830738211026052 394 PetriSTinelliF

Giblin, F.J., Glutathione: a vital lens antioxidant

P53 activates the downstream Bcl family of pro-apoptotic proteins (Bax, Bak, Bim, etc.) and reduces the number of anti-apoptotic proteins (Bcl-xl, Bcl-2, etc.), which triggers the release of Cyt-c from the mitochondria, and ultimately activates the downstream cytosolic asparagine caspases that cause apoptosis (Cederroth et al., 2024)

If headaches continue after the initial adjustment period, dropping from 500mcg to 300mcg might help

Glutathione is necessary for neutralizing ROS in the brain, which can lead to poor cognitive function