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We then applied this signature in STEP 2, an external validation set, in which it showed similar performance for distinguishing semaglutide treatment from placebo (AUC = 0.93) (Extended Data Fig
Medicaid coverage of GLP-1 drugs varies by state
Multiple ubiquitin E3 ligase genes antagonistically regulate chloroplast-associated protein degradation
These conjugates exhibited markedly enhanced degradation of EGFRdel19 under hypoxic versus normoxic conditions, establishing the feasibility of hypoxia-triggered PROTAC activation
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