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We have found, by simulation, that if we reduce the amino acid input into the system by 15%, the concentration of GSH and the synthesis rate of GSH are proportionally diminished, but there is little effect on the DNA methylation reaction, while reactions in the folate cycle are reduced by 29%
Diabetes (2011) 60:31039
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A., Merrill, P., Lokhnygina, Y., Buse, J
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