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That raises the possibility that improving overall metabolic health may be a major part of what we are seeing.
It should be noted that recent studies have shown convergence between these two pathways such that AMPK activation is an upstream event of the NRF2-mediated antioxidant response 53
Exenatide and liraglutide, which belong to the first category, have already been approved by the FDA for the treatment of T2DM
Oxidant-antioxidant balance disorders are the most important mechanisms known in the pathogenesis of this disease (141)
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