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2 A 10% to 20% reduction in basal insulin dose has been used in clinical trials
There were some misleading news articles last week that likely misinterpreted some reported data to say that GLP-1 drugs for obesity would be cost saving
In Phase 2b trials, approximately 16% weight loss was reported over 32 weeks, and multiple Phase 3 trials are planned or have begun in 2026
But in a model adjusting for the greater weight loss achieved with surgery, GLP-1s were associated with a 41 percent lower relative risk of obesity-related cancers
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