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The DIO2 gene is located on chromosome 14q31.1 and is composed of 7 exons that generate three different mRNAs through alternative promoter usage and alternative splicing
Taking oral medications at a consistent time relative to meals can help maintain predictable absorption
Most of these resolve within 4-8 weeks as the body adjusts
But in MCAS, this activation happens inappropriately, excessively, and often chronically
In the past, a watchful waiting approach was recommended in case the child grew out of having obesity, but more research has shown that this isn't as common as was thought
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