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Once it has been diagnosed and treated with antifungal medications accurately, large amounts of Candida cells are killed off rapidly known as Candida die-off or Jarisch-Herxheimer reactions

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Replicated across multiple sub-injury types

Although its efficacy is lower than methotrexate and cyclosporine, apremilasts favorable safety profile, particularly its low hepatotoxicity risk, makes it a valuable option for patients who require long-term systemic therapy and cannot tolerate immunosuppressants (Papp et al

It combines the anthropological insight of Sara Fenn with the biotechnological expertise of Philip Bromley