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Saline nebulisation induced a marked decrease in exhaled particles in the 2 patients who displayed high emission at baseline, whereas no changes was observed in the remaining

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IGF-1 C domain-modified nanoparticles (NP-IGF-1 C) promote Bcl-2 expression while activating the Akt/mTOR pathway through the binding of the IGF-1 C domain to renal tubular epithelial cell receptors, thereby inhibiting apoptosis and promoting cell proliferation, achieving a synergistic anti-apoptotic - pro-regenerative effect and significantly accelerating renal tubular repair