Grabe ka humot
During the controlled portions of 39 global HUMIRA clinical trials in adult subjects with rheumatoid arthritis (RA), psoriatic arthritis (PsA), ankylosing spondylitis (AS), Crohns disease (CD), ulcerative colitis (UC), plaque psoriasis (Ps), hidradenitis suppurativa (HS) and uveitis (UV), malignancies, other than non-melanoma (basal cell and squamous cell) skin cancer, were observed at a rate (95% confidence interval) of 0.7 (0.48, 1.03) per 100 patient-years among 7973 HUMIRA-treated subjects versus a rate of 0.7 (0.41, 1.17) per 100 patient-years among 4848 control-treated subjects (median duration of treatment of 4 months for HUMIRA-treated subjects and 4 months for control-treated subjects)
doi:10.1038/206101a0.[Crossref], [PubMed], [Web of Science ] , [Google Scholar]), suggesting that the stomach doesn't chemically alter PGN
For generic manufacturers assessing ANDA filing economics, the Cost Plus pricing data provides a useful market signal
GHK-Cu requires daily subcutaneous injection, which is a meaningful compliance requirement