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Setria Lglutathione has human data showing rises in blood glutathione within 4 to 12 weeks, with modest drops in oxidative markers in responders
Patients who supplemented with 400 mg of sublingual GSH and 200 mg of oral NAC demonstrated increases in GSH and the GSH/GSSG ratio
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GPs can prescribe B12 injections following appropriate investigation, which should include: Full blood count to identify macrocytic anaemia Serum B12 and folate levels to confirm deficiency (using laboratory-specific reference ranges) Methylmalonic acid and/or homocysteine when B12 results are borderline Intrinsic factor antibodies if pernicious anaemia is suspected Additional tests depending on clinical presentation (e.g., thyroid function, coeliac serology) When both B12 and folate deficiency are present, B12 should be replaced before folate to avoid precipitating subacute combined degeneration of the spinal cord
Optic nerve damage: Particularly in individuals with Leber's disease, a hereditary condition that causes retinal degeneration and blindness in children
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