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Kraemer et al., 2020) and altering the expression of thousands of genes, many of which are involved in the regulation of skeletal muscle structure, fiber type (Dubois et al., 2014), intramyocellular metabolism (White et al., 2013), and mRNA transcription (MacLean et al., 2008) (Figure 1)

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While coronary artery disease patients are typically older and more likely to receive beta-blockers and calcium channel blockers, DCM patients often have more severely compromised left ventricular function and are more likely to receive diuretics, warfarin, and implantable cardioverter-defibrillators [52]

10.1016/j.fct.2017.02.010 129 OktayK.BaltaciV.SonmezerM.TuranV.UnsalE.BaltaciA.et al (2015)

KY19382 combines the effects of PTD-DBM and valproic acid in a single compound