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NICE-recommended options include orlistat (available on prescription or at a lower dose over the counter), and GLP-1 receptor agonists such as semaglutide (Wegovy) or liraglutide (Saxenda) for those who meet specialist service eligibility criteria
However, the evidence from our systematic review and network meta-analysis does not allow for a direct comparison, as most included studies enrolled exclusively non-diabetic populations, without providing stratified data
doi:10.3109/14756366.2010.526769
About the Author Michael Fulks, MD, Consulting Medical Director, is board-certified in internal and insurance medicine
Weeks 8 through 12: New normal By this point, your body has largely adapted
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