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(ii) -cyclodextrins increase the kinetic stability of the spin-adduct EBN/ SG
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Elevated levels of proinflammatory cytokines (Khaibullin et al., 2017) and increased levels of chemokines responsible for recruiting peripheral immune cells and activating the adaptive immune response (Kalinowska-yszczarz et al., 2011), have been found in MS patients
Patients with higher cholesterol levels showed improved survival outcomes (log-rank, p = 0.00035), with an adjusted (age, gender, race, SOFA score within the first 24 hours, and Charlson comorbidity index) hazard ratio of 0.80 (95% CI: 0.67-0.95, p = 0.012) for high versus low cholesterol groups ( Fig
Thus, L-Arg supplementation seemed to be an attractive therapeutic strategy for cardiovascular diseases, preventing eNOS uncoupling and increasing NO synthesis in the endothelium [215, 216]
