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Clinical trials combining these agents reported 35-40% discontinuation rates when both were dosed together

Instead, they often work through different biological pathways to help the body manage energy and glucose more efficiently

Many users report a softer, smoother feel within the first 24 weeks of consistent use, with broader changes in skin tone, fine lines, and elasticity typically reported over 8 to 12 weeks

Notably, completed and ongoing studies such as NCT06475586, NCT06937060, NCT06588296, and NCT06864026 are investigating semaglutide in patients with PsO and comorbid metabolic conditions, or tirzepatide (in PsA settings), assessing dermatologic outcomes and inflammatory or metabolic markers (78, 79)

At Skinfinity Derma, our protocols are specifically calibrated for Indian skin, using appropriate laser wavelengths and mandatory pre-conditioning to minimise any risk of adverse effects