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How does the TrimRX program help manage nausea caused by GLP-1 medications

Nausea was the most common adverse event, significantly higher in the GLP-1RA group compared to placebo

In a pediatric clinical trial, there was one episode of serious suicidal ideation in a QSYMIA-treated patient requiring hospitalization and pharmacologic treatment [see Warnings and Precautions (5.2)] more patients treated with QSYMIA versus placebo reported adverse reactions related to mood (e.g., depression, anxiety) and sleep disorders (e.g., insomnia) [see Warnings and Precautions (5.4)]

Moreover, a 2024 meta-analysis suggests that ELN/NCCN recommendations may result in the undertreatment of PV patients under 60 years of age, as there is no clear evidence to support concerns that the risk of toxicity exceeds the potential benefit in reducing the risk of secondary myelofibrosis (sMF), myelodysplastic syndrome/AML, or death [17]

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