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Unlike other GH secretagogues, ipamorelin very surprisingly does not induce a significant increase in adrenocorticotropic hormone (ACTH) or cortisol levels

2013;346:f3680

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The ACAs reductions and the shift to value-based care have had some effect

Functionally, Dihexa was found to induce spinogenesis and synaptogenesis in hippocampal neurons at picomolar concentrations, indicating its ability to augment synaptic connectivity [2]

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