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Reduce the invasion and migration ability of A172 cells ( Moreover, some Chinese scholars have found that dysfunction of the mTOR signaling pathway is closely related to tumor formation, and mTOR protein is highly expressed in glioma, suggesting that abnormal mTOR signaling may be an important pathogenesis of glioma
Elsworth, B
Furthermore, the efficiency of autophagosome-lysosome fusion represents a potential bottleneck in the recycling system, dependent on Rab7 activity and its facilitation of HOPS complex assembly
FASEB J 15:11811186 Morgan MT, Nakanishi Y, Kroll DJ, Griset AP, Carnahan MA, Wathier M, Oberlies NH, Manikumar G, Wani MC, Grinstaff MW (2006) Dendrimer-encapsulated camptothecins: increased solubility, cellular uptake, and cellular retention affords enhanced anticancer activity in vitro
