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Semaglutide Side Effects (Well-Established) Common (from STEP trial data): Nausea (44%) Diarrhea (30%) Vomiting (24%) Constipation (24%) Abdominal pain (20%) Headache (14%) Serious but rare: Pancreatitis Gallbladder events (increased with rapid weight loss) Thyroid C-cell tumors (boxed warning based on animal studies) Most GI side effects are dose-dependent and improve with continued use
10.1016/j.jacbts.2018.09.004 112
ROR = 10.62, 95% CI 10.3710.86), and pancreatitis (n = 1389
Dosing : Injection Tips : Use insulin syringes
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