For systemic benefits, oral supplements are more reliable
It signals the brain to reduce hunger, supports insulin release when glucose is elevated, reduces glucagon (a hormone that raises blood sugar), and slows gastric emptying
Melasma is one of the more commonly treated concerns, and many report improvement but because melasma is hormone- and UV-driven, results are best combined with sun protection and, where relevant, hormonal evaluation
They work by mimicking the GLP-1 hormone, which: Stimulates insulin secretion in a glucose-dependent manner Suppresses glucagon release Slows gastric emptying Reduces appetite by acting on receptors in the brain It is important to note that Wegovy (semaglutide 2.4 mg) is the formulation licensed for weight management in the UK
Niacinamide Improves skin elasticity and strengthens the skin barrier while boosting radiance