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MGDs have drug-like properties, induce TPD at low compound concentrations by acting catalytically, do not require preexisting ligands for both recruited proteins and can recruit partners without drug-binding pockets 1,7,8
The pairing matters
10.1038/nri2925 Nat Rev Immunol
Notably, three mutants showed more than a 50% increase in both glutathione parameters compared to the parental strain
The exclusion criteria were as follows: Off-topic studies unrelated to HGSOC
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