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This can be life-threatening because it can stop blood from reaching parts of the lung
Lower concentrations wouldn't prevent bacterial growth effectively
Constipation becomes more common
Despite the multiple failures, the compound DS-8500a is showing promising glucose lowering properties in Phase II clinical trials without any apparent toxicological issues in clinical trials ( TGR5 Bile acids (BAs) are cholesterol-derived molecules produced in the liver and temporarily stored in the gallbladder
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10.2337/db09-0685 87
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