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Pigmentary Alterations and Benign Melanocytic Lesions of the Vulva

In rough trial comparisons, Retatrutides TRIUMPH-1 data shows around 28.3% mean weight loss at 80 weeks on the 12 mg dose, with up to 30.3% at 104 weeks in a select extension population

Monotherapy protocols are commonly initiated at 0.6 mg per week and escalated to a maximum studied dose of 4.5 mg as tolerated

Adverse events caused treatment discontinuation in 4.3%, 7.1%, 6.2%, and 2.6% of participants receiving 5-mg, 10-mg, 15-mg tirzepatide doses and placebo, respectively [49]

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