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doi: 10.1007/s40200-025-01674-w 51 SikkensECCahenDLde WitJLoomanCWvan EijckCBrunoMJ

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It has previously been suggested that mucosal immunity tends to be short-lived and that vaccines targeted to the mucosa may be less immunogenic at these sites [43], which are limitations that need to be overcome for efficacious mucosal-targeted vaccines