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[9] This is linked to the thin-fat phenotype common in South Asians: relatively higher body fat around the abdomen and lower muscle mass even at a "normal" weight

It seems clear that if treatment is to be life-long, we will need to think very hard about how we can mitigate these high rates of discontinuation and their long-term health implications

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Hence, prolonging the duration of fasting for solids could represent the optimal approach in these patients although this strategy requires further evaluation.

Northwestern Medicine