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The potential synergistic or additive interactions between these factors remain poorly understood, despite growing evidence that combined exposures may amplify oxidative stress and reproductive toxicity [103]
Pharmacokinetics: approximate terminal half-life 6 days, Cmax at 40-48 hours post-injection, steady-state in 4-5 weeks
This reframing has implications for how GLP-1 therapies are positioned, potentially reducing the distinction between diabetes and weight loss indications over time
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Understanding how these symptoms align with dose escalation is essential for optimizing adherence and minimizing treatment interruptions
