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As a busy primary care provider with the best intentions of being available to my patients when starting them on a new medication, I typically wouldnt find out about side effects or what prompted them to stop taking the drug until our next visit, months laterand by then, they had already made up their mind that they wanted to try something else

If those fail and the patient still wants to try a GLP-1 for inflammation, off-label use is reasonable with full expectation-setting