Recombinant Human Placenta Growth Factor-2 (Human PlGF-2) _ C230475 Epidermal Growth Factor (EGF) Human OPG cDNA encodes 401

Human OPG cDNA encodes 401 amino acids (aa) including a 21 aa signal peptide and a 380 aa mature soluble protein with four TNFR domains

Fibroblast growth factor was found in pituitary extracts in 1973 and then tested in a bioassay that caused fibroblasts to proliferate

LAG-1 is identical to MIP-1β (ACT II isotype) except for two amino acid substitutions

EIRNTEDLTE EWLREKLGFF H

is a member of the NGF family of neuronal and epithelial growth factors

Recombinant Human Placenta Growth Factor-2 (Human PlGF-2) _ C230475 Epidermal Growth Factor (EGF) Human OPG cDNA encodes 401PlGF 2 is an angiogenic factor that belongs to the cysteine knot superfamily of growth factors. PlGF 2 is expressed in umbilical vein endothelial cells and placenta. It signals through the VEGFR 1 FLT1 receptor, and stimulates endothelial cell proliferation and migration. PlGF 2 also signals through Neuropilin (NP 1), and can bind with high affinity to heparin. Recombinant Human PlGF 2 is a 34. 6 kDa disulfide linked homodimeric protein of two 152