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Thom NH, Meier TW, Evans PR, Leadlay PF

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This synthetic peptide derived from human gastric juice targets multiple pathways involved in fibromyalgia pain, including TNF-alpha reduction, enhanced angiogenesis, and improved mitochondrial function

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Marketed under the brand names Mounjaro (for diabetes) and Zepbound (for weight management), tirzepatide works by enhancing insulin secretion in response to meals, suppressing glucagon release, slowing gastric emptying, and reducing appetite