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"GI AEs typically occur during initiation and uptitration, appearing as transient, mild-to-moderate symptoms." Laura Schalliol, PharmD, BCACP, BCGP, Professor of Pharmacy Practice In fact, 94% of adverse events reported in major clinical trials were mild or moderate in severity

(PubMed) World Health Organization

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(More information) In iodine-deficient populations, a rapid increase in iodine intake may precipitate iodine-induced hyperthyroidism