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The authors reported that Long-R3-IGF-I disappeared rapidly from circulation after 4 hours following intramuscular administration in rats, while the related analogs Des(13)-IGF-I and R3-IGF-I remained detectable for up to 24 hours [3]

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2) It interacts with an amino acid called glutamate, to make a compound called NAGA (N-Acetyl glutamic acid)