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But others report no noticeable changes even after months of consistent use, and some experienced side effects

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Metformin : This prescription medication has a long and well-researched history of not only managing insulin resistance and age-related weight gain, but reducing inflammation, improving symptoms of menopause (such as fatigue), and even promoting longevity

180,181 Motor symptoms include progressive weakness and atrophy of proximal lower-limb muscles, leading to difficulty rising from a seated position or climbing stairs, accompanied by muscle fasciculations and hyporeflexia