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Patients should be vigilant for symptoms that might indicate their thyroid hormone levels are no longer optimal
Intraduodenal delivery of Amarasate resulted in 600% elevation from baseline of GLP-1 and CCK, and 50% elevation of PYY

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However, because Wegovy slows gastric emptying, oral medicines such as levothyroxine should continue to be taken exactly as prescribed, typically on an empty stomach before breakfast