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doi: 10.1093/plphys/kiae024 8 CaoX.WangS.GeL.ZhangW.HuangJ.SunW

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Nrf2 depletion in macrophages leads to increased foam cell formation, increases the M1 inflammatory phenotype with enhanced expression of pro-inflammatory monocyte chemoattractant protein-1 and interleukin-6, and aggravates atherosclerosis (244, 245)

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Fatigue: Feeling tired or even exhausted is a common side effect