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Combined in-vivo studies in rodent musculoskeletal-injury models examining whether co-administration alters repair time-course versus single-peptide arms
These findings suggest that intranasal GHKCu has the potential to attenuate features of AD, including cognitive decline, amyloid plaque accumulation, and neuroinflammation, and provide the rationale for further studies in aging mice, for example using an AAV vector containing sequences of A42 and mutant tau [48]
Mohasseb M, S E, Ma Y, N H (2011) Testicular oxidative damage and role of combined antioxidant supplementation in experimental diabetic rats
Zhai et al., 2024)
Future research applications will likely expand to include investigation of senescence heterogeneity, tissue-specific senescent cell populations, and the development of personalized approaches to senolytic intervention based on individual senescent cell burden and characteristics
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