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Studies have shown that when GLUT1 is overexpressed, there is an increase in glucose uptake in cardiomyocytes and an increase in glycogen accumulation, and the metabolic pattern shifts to glycolysis, promoting cardiomyocyte proliferation (62)

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CD4 CD4 is a critical protein of the adaptive immune system, which may be expressed on the surface of some lymphocytes, including T helper cells, monocytes, macrophages, and dendritic cells

Because these two pathways operate through different receptor systems and intracellular signalling cascades, they can have synergistic effects when studied in combination