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The effects of D2R-DAT disruption on extracellular dopamine Next, we performed an in vivo microdialysis study to investigate whether the disruption of D2R-DAT protein complex by TAT-DAT NT increases extracellular level the nucleus accumbens core (NAc), part of the ventral striatum, which can explain the stimulant effects of TAT-DAT NT observed previously

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The former generally refers to the biphasic dose-response effects of single, often isolated, bioactive compounds (hormetins), such as resveratrol or curcumin